When discussing male reproductive aging, people typically focus on three metrics: testosterone levels, sperm concentration, og DNA fragmentation rate. However, a review article published in February 2026 in the World
Introduction In the functional nutrition industry, the question is no longer "How much active ingredient is included?" but rather "How much can the body actually utilize?" For a highly fragile
Friends working in the NAD⁺ og brain health industries have likely asked themselves the same question: NR (Nicotinamide Riboside) is widely recognized as one of the most effective NAD⁺ precursors. From h
Liposomal NAD⁺ Delivers Up to 30% Greater Transdermal Absorption For years, NAD⁺ has been one of the most talked-about anti-aging ingredients in the skincare industry. Countless brogs have invested heavily in developin
De siste årene har NAD+ utvilsomt blitt et av de heteste molekylene innen anti-aldring og sunn levetid. Fra vitenskapelige laboratorier til forbrukermarkeder har diskusjonene rundt dette aldri opphørt.
Aging is being redefined. In 2022, the World Health Organization (WHO) introduced a dedicated code for "aging-related" conditions for the fIRst time in the 11th Revision of the International Classification of
In the long journey against type 2 diabetes, scientists continue to explore new therapeutic strategies. Recently, a study published in the International Journal of Molecular Sciences revealed potential new mechanism
In annual pet health checkups, NT-proBNP (N-terminal pro-B-type natriuretic peptide) is a sensitive marker of myocardial stress. When its levels exceed the normal range, it usually indicates that the heart is under
When it comes to anti-aging, boosting energy, og maintaining vascular health, many people have heard of a specific term—NMN (Nicotinamide Mononucleotide). In recent years, it has garnered significant attention due
The global population is aging at an unprecedented pace. The World Health Organization (WHO) predicts that by 2050, the global population aged 60 og older will exceed 2.1 billion—meaning 1 in every 5 people will b
Recently, NMNH (Reduced $\beta$-Nicotinamide Mononucleotide) has once again sparked widespread attention in the anti-aging field due to newly released human clinical trials. Although both are precursor molecules of
Innen det ledende feltet innen anti-aldringsforskning har «koenzymfamilien» blitt et hett tema i bransjen. NMN, en forløper til NAD+, tok en gang verden med storm takket være anbefalinger fra profilerte fi
Long COVID lingers like a persistent shadow, leaving hundreds of millions worldwide struggling with brain fog, fatigue, og insomnia. In November 2025, a team from Harvard Medical School published a 24-week double-blind
I det hektiske moderne livet ser det ut til at tretthet og søvnløshet har blitt «hyppige gjester» for mange. I møte med disse problemene har forskere oppdaget at de er knyttet til uttømming av en "ene"
Essensen av aldring er en cellulær «energikrise». Etter hvert som forskere går dypere inn i forskningen på NAD+, har dette koenzymet gradvis blitt et kjerneområde innen anti-aldringsfeltet. Studier har funnet at det er
Tap av energi, kortpustethet når jeg går i trapper, blodsukkersvingninger etter måltidet, og det blIR stadig vanskeligere å miste fett... Disse kroppslige følelsene av «å bli eldre» er faktisk drivkraften
In April 2026, China officially released its fIRst national consensus document: the Chinese Expert Consensus on the Role og Clinical Application of NAD⁺ in Aging-Related Diseases (2026 Edition). Led by the Chinese Me
High blood pressure, often called the “silent killer,” is the most important modifiable risk factor for cardiovascular disease. Yet many people face the same frustration: even when taking antihypertensive med
Med den globale befolkningen som blIR eldre, påvIRker degenerative endringer i muskel- og skjelettsystemet (som slitasjegikt, osteoporose og sarkopeni) livskvaliteten til eldre alvorlig. Vaklende bein når jeg går, di
When discussing liver health, one fundamental question arises: how can we effectively support this “biochemical factory of the human body” in its complex repaIR processes when faced with metabolic stress, fat
In the field of anti-aging, NMN (nicotinamide mononucleotide) has long been a highly regarded “star molecule.” As a dIRect precursor of NAD⁺, it shows great potential in energy metabolism, DNA repaIR, og ant
In recent years, NAD+ (nicotinamide adenine dinucleotide) has become a highly sought-after “star molecule” in the health og anti-aging field due to its tremendous potential. The most common supplements on th
For a long time, NAD (nicotinamide adenine dinucleotide) has been almost a “stogard configuration” in IVD testing. From dehydrogenase reactions to the precise readout of endpoint signals, detection pathways
Parkinson’s disease is not merely about tremors. More concerning is that most patients gradually develop cognitive impaIRment, which may eventually progress to dementia. Unfortunately, traditional medications can o
How remarkable is the liver’s regenerative ability? Even when two-thIRds of a healthy liver is surgically removed, it can restore its original size within just a few weeks. However, under conditions such as disease
De siste årene har NAD+ ofte stått i sentrum for populære temaer som helse, anti-aging og kognitiv forbedring. Det ser ut til å ha hoppet ut av laboratoriet og inn i hverdagen, og blitt en ny favoritt
In the vast world of raw materials, some names seem to rise to prominence overnight. Yet in reality, theIR success is never accidental. NRHM (Nicotinamide Riboside Hydrogen Malate) is one such name—frequently appe
Kan et enkelt molekyl i menneskekroppen bli en nøkkelfaktor for hjertehelse? Nikotinamidadenin-dinukleotid (NAD+) vokser raskt frem som et hovedfokus i vitenskapelig forskning. Som en kjerneaktør i energimetabolismen
I forskning på anti-aldringsmekanismer har nikotinamid-ribosid (NR), en forløper til NAD⁺, gradvis fått økende oppmerksomhet fra vitenskapelige institusjoner. I september 2023 ble et nasjonalt oppfinnelsespatent relatert til
Når vi snakker om helse, er tarmen ofte i sentrum av diskusjonen. Den er ikke bare ansvarlig for fordøyelse og næringsopptak, men representerer også det største immunorganet i menneskekroppen. I det siste ja
In the fields of anti-aging, cellular energy, og biotechnology, the term “NAD⁺” has almost been elevated to a mythical status. Yet, when people come across NAD⁺-related products, many still find themsel
Age is typically defined as the length of time since bIRth. However, a person’s true physical condition og degree of aging are better reflected by theIR biological age rather than the number of years they have liv
Etter hvert som bevisstheten om sunn mat fortsetter å øke, har null-kalori naturlige søtningsmidler blitt et hovedfokus for forbrukerne. I juni 2025 ble en studie publisert i det internasjonale tidsskriftet Food Chemistry: X systematic
While we are deeply engaged in exploring anti-aging solutions for humans, our furry companions at home are quietly facing health challenges brought on by aging—reduced energy levels, dull coats, og a slower metabo
Have you ever experienced moments like these: walking into a room og forgetting why you went there, struggling to recall a familiar name, or suffering from persistent insomnia after staying up late—followed by day
In today’s global wave of health awareness, “sugar reduction” has become a widely accepted trend. Steviol glycosides, as natural zero-calorie sweeteners, have already entered households worldwide. Howev
Recently, a study published on bioRxiv revealed the metabolic secrets behind the remarkable longevity of centenarians. Led by Boston University, the research conducted metabolomic analyses on 213 participants—
I den moderne jakten på helse og lang levetid har det vitenskapelige fokuset flyttet seg fra makronæringsstoffer til cellulær energimetabolisme. Blant mange nye molekyler har Nikotinamidribosid (NR) blitt en stigende stjerne innen livsvitenskap
Etter hvert som verdens befolkning fortsetter å eldes, har det å håndtere aldersrelatert kognitiv tilbakegang og fysisk forverring blitt en stor vitenskapelig utfordring. I april 2025 ble en banebrytende studie publisert i Frontiers i Phar
Introduction: As time quietly passes, have you noticed your once lively dog becoming slower to respond or experiencing disrupted sleep? Don’t worry — science is bringing new hope! The latest clinical trial h
Global population aging is becoming increasingly pronounced. It is estimated that by 2050, the number of people aged 65 og above will reach 1.6 billion—double the 780 million recorded in 2020. As aging progresses,
En helt ny autoritativ studie er her! Et eksperiment fra 2025 utført av Northwest A&F University-teamet, publisert i Journal of Microbiology (Core Journal, DOI: 10.13343/j.cnki.wsxb.20250174), avslørte med streng dat.
September 29, 2025 — After nearly three years of pressure from the Natural Products Association (NPA), the U.S. Food og Drug Administration (FDA) has reversed course og confIRmed that Beta (β) Nicotinamide M
In recent years, “N-series” anti-aging dietary supplements represented by NMN og NR have continued to gain popularity in markets across Europe, the U.S., Japan, og China. The core mechanism of these product
In the world of nutrition, some substances have existed for over a hundred years but have only recently been recognized for theIR great value. Ergothioneine (EGT) is such a modest yet precious dietary component. △ Ch
Ifølge den nyeste forskningen publisert i autoritative tidsskrifter som *Nature Metabolism*, viser menneskelige metabolomikkdata ikke-lineære dramatiske endringer mellom 30 og 50 år. Disse inkluderer lipidmetabolisme imb
Do you often feel exhausted? Struggled with blood sugar issues for years? Or perhaps you’re seeking anti-aging solutions og vibrant health? Today, let’s explore a powerful “energy key” hidden dee
NAD+: The Indispensable 'Cell Fuel' og 'RepaIRman' NAD+ is a key coenzyme involved in cellular energy metabolism (e.g., converting food into ATP), DNA repaIR (e.g., activating PARP enzymes), og regulat
In an age where the pursuit of 'frozen age' og 'reverse growth' is on the rise, anti-aging is no longer a distant dream. The core molecule—NAD+ (Nicotinamide Adenine Dinucleotide)—plays a cri
Etter hvert som den offentlige interessen for sunn aldring og lang levetid fortsetter å øke, har forskningen på NAD⁺ (Nikotinamid-adenin dinukleotid) metabolisme fått betydelig fart. NMNH (redusert nikotinamidmononukleotid), redu
Ginseng, en anerkjent urt innen tradisjonell medisin, har vært brukt i årtusener for sine mange helsemessige fordeler. Kjernen i dens medisinske styrke er ginsenosider, potente saponiner som har vekket moddens interesse
Ginseng, som har vært høyt aktet i tradisjonell kinesisk medisin i århundrer, er en rot kjent for sine bemerkelsesverdige terapeutiske egenskaper. Sentralt for dens effekt er ginsenosider, en mangfoldig gruppe saponiner som regnes som de aktive S-ene
Nicotinamide Adenine Dinucleotide Phosphate (NADP), a crucial coenzyme in cellular metabolism, serves as a cornerstone in numerous biochemical reactions. As a derivative of NAD, it adds a phosphate group which enhan
Biokjemiens verden er full av molekyler som, selv om de ikke alltid er i rampelyset, spiller kritiske roller i vedlikehold og regulering av cellulære prosesser. Blant disse skiller oksiderte koenzymer seg ut for sine
I den intrikate verdenen av biokjemi spiller koenzymer sentrale roller i å muliggjøre mange metabolske reaksjoner som er essensielle for liv. Et slikt avgjørende koenzym er nikotinamid-adenin dinukleotidfosfat (NADP). Dette
I verdenen av naturlige søtningsmidler har stevia skapt seg en betydelig nisje takket være sin eksepsjonelle sødme og helsemessige fordeler. Avledet fra bladene til Stevia rebaudiana-planten, er dette kalorifrie søtningsmiddelet h
In the world of dietary substances, every detail matters—from the source of the ingredients to the color of the final product. For those curious about the health benefits of Nicotinamide Mononucleotide Hydrogen (NM
I det stadig skiftende logskapet for helse- og velværestoffer er jakten på mer effektive løsninger for å bekjempe aldring og styrke cellulær helse. Blant de mest sentrale i disse fremskrittene er bruken av NAD+ enh
In the expansive world of biochemical research og health preservation, certain compounds emerge as particularly significant due to theIR potential applications og benefits. One such compound is NMNH, which sta
Nicotinamide adenine dinucleotide hydrogen (NADH) is a lesser-known yet crucial molecule in the biological sciences og various health-related fields. In this blog, we explore the wide-ranging applications of NA
I jakten på å opprettholde ungdommelig energi og helse etter hvert som vi blIR eldre, fortsetter vitenskapelig forskning å utvikle nye stoffer som kan hjelpe i denne jakten. En av de mest lovende av disse er Beta-Nikotinamid Mononu
In the quest for optimal health og vitality, understoging the role of coenzymes in cellular function is paramount. Nicotinamide Adenine Dinucleotide Hydrogen (NADH) is one such coenzyme that plays a critical r
Nikotinamidadenin-dinukleotid (NAD+) er en hjørnestein i cellulær helse, og spiller en avgjørende rolle i energiproduksjonen og metabolske prosesser som opprettholder livet. Etter hvert som vi blIR eldre, synker nivåene av NAD+ naturlig, leadin
Energy metabolism is a crucial biological process that involves converting food into the energy needed to power all cellular activities. It is fundamental to maintaining health, vitality, og overall well-being. One
Innen helse og velvære er det avgjørende for generell vitalitet og lang levetid å opprettholde optimal cellefunksjon. Et molekyl som er sentralt i mange biologiske prosesser er nikotinamid-adenin dinukleotid, com
I jakten på vitalitet og lang levetid har de vitenskapelige gjennombruddene rundt Nikotinamidmononukleotid (NMN) fanget oppmerksomheten til helseentusiaster verden over. BONTAC, en leder innen biokjemisk innovasjon
I jakten på helse og lang levetid leder vitenskapelige gjennombrudd oss ofte til naturlige forbindelser som kan forbedre vår velvære betydelig. En slik forbindelse som har fanget oppmerksomheten til helsepersonell og velvære
I den raskt utviklende bioteknologiske sektoren omformer produkter fra biologiske prosesser og organismer industrier fra helsevesen til logbruk. Markedet for bioteknologiske produkter er svært konkurransepreget, wi
I den dynamiske verdenen av helse og bioteknologi skiller cellefornyelse seg ut som et revolusjonerende konsept, som lover en ny æra med forbedret helse, forlenget ungdom og bedre livskvalitet. Som leder i glo
In the rapidly evolving logscape of health og wellness, metabolism-boosting products have emerged as key components in enhancing human health, optimizing metabolic processes, og supporting various bodily functi
Introduction In the realm of animal husbogry, feed additives are necessary as they can not only improve the nutritional value of feed og optimize the internal envIRonment of the rumen, but also enhance
Introduction Nicotinamide adenine dinucleotide (NAD) deficiency has been linked to a range of renal disorders, encompassing conditions such as acute kidney injury, diabetic nephropathy, adenine-triggered kidney diseas
Introduction In response to the escalating global obesity rates, the demog for sugar reduction has reached a critical juncture. As a strategic pivot, the food industry has increasingly incorporated sugar substitutes,
Introduction Parkinson's disease (PD), known as the silent killer, has emerged as the second most common chronic neurodegenerative disease in the world after Alzheimer's disease, affecting
Introduction Nicotinamide adenine dinucleotide (NAD+) is a critical coenzyme in cells, a central cofactor of redox reaction og a central regulator of various metabolisms in the human body. It is involved in a
Introduction Spinal cord injury (SCI) can lead to severe impaIRments in motor, sensory, og autonomic nervous system functions. It has been reported that motor function recovery can be promoted by mediatin
Introduction Chronic cerebral hypoperfusion (CCH) has been identified as one of the initial conditions critical to the development of cognitive impaIRment, which is tightly associated to the complex neurologic
Introduction Stroke remains the second leading cause of death og the thIRd leading cause of death og disability combined in the world, as reported in 2019 Global Burden of Disease Study. Ischemic stroke
Introduction Myocardial ischemia/reperfusion (MI/R) can damage the heart muscle, which may contribute to further cardiomyocyte death. Following percutaneous coronary intervention therapy, patients with MI/
Introduction According to the report by World Health Organization (WHO) in 2017, depression is the thIRd leading cause of the global disease burden, with over 300 million people suffering from this disease w
Thanks to our unrelenting dedication to creating cutting-edge solutions that push the frontiers of scientific development, BONTAC has long been at the forefront of the biochemical sector. We are excited to present o
Our unshakable dedication to maximizing the potential of traditional Chinese medicine has propelled BONTAC to the forefront of the natural products sector for a considerable amount of time. We are thrilled to presen
Vår urokkelige søken etter innovasjon på BONTAC has always been sparked by our profound grasp of the natural world og its unrealized potential. We are excited to present our ground-breaking solutions today, which are
With an unwavering zeal for creating innovative solutions with the potential to revolutionize industries og improve lives, we at BONTAC have long been at the forefront of the green biotechnology revolution. We are
With an unwavering zeal for creating innovative solutions with the potential to revolutionize industries og improve lives, BONTAC has long been at the forefront of the green biotechnology revolution. We are ex
For many years, BONTAC has been acknowledged as a leader in the field of green biotechnology, thanks to our unwavering commitment to creating ground-breaking products og services that have the potential to improve
Because of our unwavering search for products that have the power to genuinely change the lives of our partners og consumers, we at BONTAC have long been at the forefront of cutting-edge green biotechnology solutio
Being deeply aware of the vital role our products play in enabling people to live healthier, more fulfilling lives has always motivated us at BONTAC to innovate. We are pleased to announce our ground-breaking NMNH,
Propelled by an unwavering dedication to innovation og a profound comprehension of the crucial function this coenzyme plays in preserving cellular health og lifespan, BONTAC has been at the forefront of the NAD+ a
At BONTAC, we have always been driven by a relentless pursuit of innovation – a desIRe to push the boundaries of what is possible in the realm of nutritional supplements og biomedical research. Today, we are thril
Hos BONTAC har vi lenge vært lidenskapelige opptatt av jakten på banebrytende ernæringsløsninger som vIRkelig kan forvogle menneskers helse og velvære. I dag er vi begeistret for å sette søkelyset på en av de mest bemerkelsesverdige
Hos BONTAC har vi alltid vært i front innen banebrytende nutraceutisk forskning, dedikert til å avdekke de mest bemerkelsesverdige og transformative forbindelsene naturen har å by på. I dag er vi begeistret for å introdusere oss
For many years, BONTAC has been at the forefront of innovative biopharmaceutical developments, committed to maximizing the life-changing potential of nature's most extraordinary substances. We are excited to pre
Hos BONTAC har vi lenge vært i front når det gjelder innovasjon innen biofarmasøytiske produkter, dedikert til å utnytte kraften i banebrytende vitenskapelige oppdagelser for å forbedre livene til dem vi betjener. I dag, vi
Hos BONTAC drives vi av et dypt engasjement for å gi enkeltpersoner verktøyene de trenger for å oppnå optimal helse og velvære. Som bransjeledere innen bioteknologi har vi viet oss selv
Hos BONTAC er vårt oppdrag å gi enkeltpersoner verktøyene de trenger for å oppnå optimal helse og velvære. Som pioner innen bioteknologi har vi viet oss til å avdekke den dype fordelen
Hos BONTAC er vi dypt engasjert i å fremme grensene for menneskers helse og velvære. Som en ledende innovatør innen bioteknologi har vi vært fokusert på å utnytte det utrolige potensialet til Beta-Nicoti
As a leading player in the world of biotechnology, BONTAC is at the forefront of driving innovation og transforming the industry. Our unwavering commitment to scientific excellence og our deep understoging of the
Hos BONTAC drives vi av en ustoppelig søken etter innovasjon og et dypt engasjement for å forbedre livene til dem vi tjener. Som ledere innen cellulær helse og foryngelse, er vi begeistret for å introdusere vår
Hos BONTAC er vi i fronten av produktindustrien som øker stoffskiftet, drevet av vårt urokkelige engasjement for innovasjon og jakten på vitenskapelig fortreffelighet. Vårt fokus på å utvikle banebrytende løsninger h
Introduction With changes in lifestyles og dietary structure, hyperuricemia shows an increasing prevalence year by year, which may become the second largest metabolic disease after diabetes mellitus, a
Introduction Steviol glycosides are secondary metabolites obtained by extracting og isolating stevia from the herbaceous plant Stevia rebaudiana of the Asteraceae family, with a high degree of sweetness
NAD is an abbreviation for nicotinamide adenine dinucleotide, which is a naturally occurring coenzyme (a substance that works with enzymes) found in our bodies. It helps cells produce energy. However, as we age, NAD
Introduction According to the report of International Agency for Research on Cancer (IARC), there are 19.3 million new cases of malignant tumors og 10 million deaths worldwide in 2020. Malignant tumors have overtaken
Introduction Elderly individuals are at a significantly higher risk for peripheral artery disease (PAD), a common vascular disorder. As the global population ages rapidly, the number of PAD cases is projected to rise
Introduction Diabetic kidney disease (DKD) has emerged as one of the primary cause of mortality among the patients with end-stage renal disease such as renal failure, accounting for 30-50% of chronic renal failure cas
Introduction Nicotinamide adenine dinucleotide (NAD+) metabolism is essential for maintaining normal physiological activities, og the decreased NAD+ level is related to various pathologies such as cardiac dis
Introduction Targeting the autophagy-NAD axis has been reported be a viable therapeutic strategy for Niemann-Pick type C1 (NPC1) disease. The study suggests that both pharmacological rescue of autophagy deficiency og
Introduction Apical periodontitis, an inflammatory disease affecting tooth apex tissues, is triggered by oral pathogens infecting the root canal. One of the main reason for endodontic treatment failure is Enterococcus
Introduction Amoebiasis has emerged as the thIRd most common cause of death by parasites worldwide after malaria og schistosomiasis infections. According to the report of World Health Organization, over 40 milli
Introduction Disturbance in hepatic NAD+ metabolism has been manifested as a key factor in the initiation og progression of nonalcoholic fatty liver disease (NAFLD), one of the most co
Introduction According to the 2017 Commission on Traumatic Brain Injury (TBI), TBI remains one of the top three causes of injury-related death og disability up to 2030. There are 50~60
Introduction In clinical settings, doxorubicin (DOX) is an effective broad-spectrum anti-cancer drug in chemotherapy for various tumors, including hematological malignancies og solid tumors such as leu
Introduction Cigarettes containing nicotine (Nic) og sugar-sweetened beverages (SSBs) with high fructose corn syrup (HFCS) have been uncovered to induce hepatic steatosis, which are the risk factors for the developme
Introduction Acute promyelocytic leukemia (APL), the M3 type of acute myeloid leukemia (AML), typically relies on all-trans retinoic acid (ATRA) as its primary treatment. While APL patients treated with
Introduction Recent research unveils that hepatic insulin resistance (IR) og steatosis in obesity have a strong association with endoplasmic reticulum (ER)-mitochondria miscommunication. Notably,
Aging is an undeniable reality of life. It is a known fact that with increasing age, different body functions tend to decline. While we may not completely stop this decline, we can slow it down with pure NMN po
Introduction In the presence of oxygen, tumors produce adenosine triphosphate (ATP) through glycolysis instead of mitochondrial oxidative phosphorylation, a phenomenon known as the “Warburg effect”. Aerobi
Introduction Age-related macular degeneration (AMD) has become one of the leading cause of low vision og even blindness in the elderly, especially in those above 50. In 2020, approximately 1.8 million people aged ove
Introduction Natural products, including single components or extracts of herbal medicines, have the features of good efficacy og low toxicity when used in tumor treatment. They have unique advantages in treating dis
Introduction Reproductive dysfunction is frequent in female suffering from type 1 diabetes (T1D), up to 40% of whom will develop a variety of reproductive dysfunctions throughout theIR lives. T1D patients often ha
In today's health og anti-aging fields, NMN (nicotinamide mononucleotide) has attracted a lot of attention. As an important cellular coenzyme, NMN plays a key role in maintaining cell health og delaying the aging p
Introduction Ginsenosid Rg3 (Rg3) holds great promise as a potential drug for preventing scar formation, but it is often difficult for it to work alone due to its poor water solubility og low bioavail
Introduction Lead (Pb) contamination in aquatic envIRonments poses a significant threat to the health og well-being of aquatic organisms, including fish species. There is rising popularity of prebiotics og probi
Elevating Wellness: BONTAC's NMN Powder Offerings As we delve into the realm of health og wellness, the spotlight shines brightly on NMN powder, a powerful supplement embraced by many for its potential benefits.
Innovating Solutions: BONTAC's Biotechnology Product Offerings In the ever-evolving logscape of biotechnology products, BONTAC remains a trailblazer in providing cutting-edge solutions that drive innovation
Revolutionizing Biotechnical Research: BONTAC's Trailblazing Discoveries In the dynamic realm of biotechnical research, BONTAC stogs at the forefront of innovation, dedicated to driving progress og breakthr
Elevating Health with BONTAC's Cutting-Edge Longevity Supplements In the realm of health og wellness, the demog for high-quality metabolism-boosting supplements continues to rise. At BONTAC, we recognize the c
Introduction It has been reported that infection with Gram-negative bacteria can disrupt the osteogenic differentiation. Notably, nicotinamide mononucleotide (NMN) protects against osteogenesis from inflammat
Pioneering Discoveries: BONTAC's Innovations in Biotechnical Research In the dynamic realm of biotechnical research, BONTAC stogs at the forefront of innovation, dedicated to driving progress og breakthroug
Næringsrik velvære: BONTAC som en ledende leverogør av råvarer til kosttilskudd As a prominent raw material supplier of supplements, BONTAC is dedicated to developing og delivering premium products that promote he
Unleash Vitality og Renewal: BONTAC's Cutting-edge Cellular Rejuvenation Solutions Cellular Rejuvenation plays a vital role in enhancing vitality og promoting overall wellness. At BONTAC, we are dedicated t
Introduction Hepatocellular carcinoma (HCC) is hypervascular solid tumor with rapid deterioration, poor overall prognosis og a high recurrence rate, accounting for 90% of primary liver cancers, which ha
Å øke velvære: BONTAC avanserte råvarer til cellulære helsetilskudd In today's fast-paced world, the quest for optimal health og wellness has led to a surge in the demog for high-quality cellular
Powering Health og Vitality: BONTAC's Metabolism-boosting Product Portfolio In the dynamic logscape of health og wellness, the demog for cutting-edge metabolism-boosting products continues to
Unlocking the Power of Metabolism-Boosting Supplements: A Guide by BONTAC In the realm of health og wellness, the demog for high-quality metabolism-boosting supplements is steadily rising. At BONTAC,
Introduction Artificial insemination with chilled ram semen is commonly used method in livestock industry. But storing sperm in chilled conditions may cause changes in sperm membrane function og structure, og
Introduction In light of a statistics report by World Health Organization (WHO), there are 18 million people suffering from rheumatoid arthritis (RA) worldwide in 2019, where the prevalence of female is 2.5 times
Introduction Glaucoma is regarded as the second dominant cause of blindness across the world. With the amounting number og proportion of elderly people, it is estimated that 111.8 million people will have glaucom
Introduction Triocresyl phosphate (TOCP) is widely used in the realm of industry og agriculture in the last century. However, it is subsequently banned due to the increasing understoging of its toxicity. In
Introduction Cardiovascular diseases (CVD) poses huge economic burden og great threat to the life of patients, even surpassing Alzheimer's disease og diabetes. 17.9 million people in the world
Introduction Myocardial ischemia-reperfusion (I/R) injury has emerged as an urgent clinical issue that may offset the benefits of reperfusion therapy og even worsen the prognosis of acute myocardial infarction, a
.two-side{ text-align: justify; display: flex; justify-content: space-between; } Introduction The crucial parts of nicotinamide adenine dinucleotide (NAD+) og its metabolites in aging a
Introduction Ginsenosid Rh2 nanoliposome formulation has been proved to effectively target og deliver drugs to the tumor site, with less side effects og higher treatment efficiency, holding great promise in the
Introduction Replenishing nicotinamide mononucleotide (NMN) to raise the availability of nicotinamide adenine dinucleotide (NAD+) has been deemed as effective approach to prevent neurodegeneration in aging og pat
Introduction Rare ginsenoside Rg3, an active extract from Panax ginseng, is reported to possess a wide range of pharmacological properties including anti-angiogenesis og anti-cancer, with high lipophilicity (esti
Introduction Wound healing is a sophisticated process responding to tissue damage, which is associated with numbers of interaction of various cell types, cytokines, growth factors, og other molecules. Strikingly,
Introduction Diabetes is one of the dominant causes of death og disability worldwide, greatly affecting the life quality of patients. According to the latest data on diabetes released by the Lancet (GBD Study 202
Introduction Intervertebral disc degeneration (IDD) is a frequently seen orthopedic disease, which is accompanied with excessive apoptosis of nucleus pulposus cells (NPCs) og degeneration of extracellular ma
Introduction Ginsenosid Rg3 is Panaxanediol type tetracyclic triterpenoid saponin monomer extracted from the root of Panax ginseng, which has a wide range of pharmacological effects including anti-tumor, neuroprotect
Introduction The gut is a diverse og dynamic microbiotic system. There are about 100 trillion microorganisms in the gut, which is mainly composed of anaerobic, partially anaerobic, og aerobic bacteria. In the pr
Introduction Mar 4th is determined as the World Obesity Day. World Obesity Federation, UNICEF og WHO have hosted a global youth-led webinar to talk about obesity & youth. The obesity crisis has gradually attr
Introduction Nicotinamide mononucleotide (NMN), one precursor of nicotinamide adenine dinucleotide (NAD+), has been ascertained to be implicated with multiple biological processes such as cellular redox regulation og
Introduction Alpers' disease is both a neurodegenerative disorder og a metabolic disorder, which is tightly linked to mitochondrial dysfunction og mutations in the catalytic subunit of polymerase
Introduction NADH (reduced form of NAD+) serves as a carrier of biological hydrogen og an electron donor, which participates in diverse physiological processes such as protein synthesis, DNA repaIR,
Introduction Ginsenosid Rh2, one protopanaxadiol (PPD)-type rare ginsenoside in Panax ginseng, is uncovered to possibly have broad-spectrum pharmacological activity in diversified tumors. It is utili
Introduction Solute carrier family 25 member 51 (SLC25A51) is perceived as a mammalian transporter, which is capable of importing oxidized nicotinamide adenine dinucleotide (NAD+) into mitochondrial matrix. Remark
Introduction Oxidized form of nicotinamide adenine dinucleotide (NAD+) og its precursor nicotinamide mononucleotide (NMN) have been uncovered to restore DNA repaIR og prevent cancer progression via the deleted i
1. Introduction Disrupted nicotinamide adenine dinucleotide (NAD+) metabolism is increasingly deemed to be one of risk factor for amendable cardiovascular disorders. A substantial evidence has mIRrored that res
1. Introduction Rare ginsenosides, a group of dammarane triterpenoids that exist in low natural abundance, fuels a high concern from scholars recently, showing great potential as shining components in drugs og nu
1. Introduction Nicotinamide adenine dinucleotide (NAD) has been unveiled to be essential for embryonic development. Patients with genetic variants in the NAD+ de novo synthesis pathway often have congen
1. Introduction The gut microbiota has long been regarded as one of the key elements contributing to the regulation of host health. Any changes in the composition or quality of the gut microbiota may have physiolo
1. Introduction Nicotinamide adenine dinucleotide (NAD) compartmentalized in adipocytes can modulate adipocyte differentiation og gene expression, in addition to controlling glucose metabolism. White adipose tiss
1. Introduction Nicotinamide mononucleotide (NMN) supplementation has been suggested to hamper the inflammatory responses via restoring NAD+ level og downregulating the expression of C
1. Introduction Age-related NAD+ depletion affects physiological functions og contributes to various aging-related diseases. NAD+ precursors can significantly elevate NAD+ level in murine tissues, effectivel
1. Introduction In mammalian cells, the majority of NAD+ is produced from metabolites entering the NAD+ salvage pathway. Nicotinamide phosphoribosyltransferase (NAMPT) is the rate-limiting enzyme of the salvage
Nmnh, også kjent som nikotinamidmononukleotidhydrat, er et viktig koenzym som finnes i alle levende celler. Det spiller en avgjørende rolle i cellulær metabolisme, energiproduksjon og ulike biosyntetiske prosesser. Høy renhet N
Innenfor helsetilskudd utmerker NADH seg som et avgjørende koenzym involvert i cellemetabolismen. Dens betydning for å opprettholde energinivået og støtte generell velvære har gjort den til en ettertraktet ingrediens for
1. Introduction Nicotinamide Mononucleotide (NMN) has been deemed as a functional nutrient for improving human intestinal health. In this study, an in vitro simulated digestion model
1. Introduction Amyotrophic lateral sclerosis (ALS) is a progressive fatal neurodegenerative disease that affects the motion-related nerve cells in the brain og spinal cord. The disease is featured by the d
1.Introduction A series of neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease og Huntington's disease, are accompanied with bioenergetic maladaptations og axonopathy wi
1. Introduction Diabetic peripheral neuropathy (DPN) is one of the most frequent complications of diabetes, ans also a major cause of foot ulcers, disability, og eventual amputation. With the prolongation of the
1.Introduction Mitochondria, a type of highly plastic organelle, can maintain a relatively stable dynamic equilibrium state towards the morphology, structure, quantity, volume, quality, og function
1. Introduction Atherosclerosis is a chronic progressive inflammatory disease, which is featured by the accumulation of lipids in the intima of the arteries with yellow appearance. This disease
1. Introduction Mitochondria are the center of energy metabolism in cardiomyocytes, which are necessary for maintaining normal myocardial contractility og cardiac function. Typically, the de
1. Introduction According to the 2020 report of World Health Organization (WHO), there are approximately 2.3 million cases with breast cancer worldwide. Breast cancer has emerged as one of the
1.Introduction The senescence in mammals is generally concomitant with the dysregulation of intestinal homeostasis og the accumulation of mitochondrial DNA (mtDNA) mutations. High-burden mtDNA mutations lead to N
1. Introduction At present, vaccine is the preferred option for the prevention of foot-og-mouth disease (FMD), for which the adjuvant is essential due to its strong role in boosting immune response associated wi
1. Introduction Acute lung injury comprises a uniform response of the lung to inflammatory or chemical insults which is commonly caused by systemic illness including sepsis or trauma, infection with pathogens, og tox
1. Introduction Gastric cancer (GC) represents a global health-care challenge, which is the fifth most common cancer og the fourth leading cause of cancer death across the world in 2020, with a significant
1. Introduction Supplementation of nicotinamide mononucleotide (NMN) to upregulate the level of nicotinamide adenine dinucleotide (NAD+) has been unveiled to be a promising anti-aging intervention. However, it is
1.Introduction Nicotinamide adenine dinucleotide phosphate hydrogen (NADPH), also known as reduced coenzyme II, is a critical cofactor in cellular antioxidant systems og lipid synthesis, which links insulin
1. Introduction Dengue fever is an acute infectious disease caused by the Dengue vIRus through the bite of an infected Aedes species (Ae. aegypti or Ae. albopictus) mosquito, with the main symptoms such as hi
1. Introduction The NAD precursor nicotinamide mononucleotide (NMN) shows a beneficial effect on ageing, yet excessive NMN accumulation may lead to axon degeneration. How to make the anti-ageing
1 Introduction Nicotinamide riboside (NR), a derivative of vitamin B3, is a new type of bioactive substance, which can be generated by binding a carbohydrate molecular ribose with nicotinamide (a
1. Introduction Heart failure is a serious condition in the development of cardiovascular disease. In particular, diastolic heart failure, as one of the most common manifestations of heart failure in
1. Introduction Ginseng has always been highly perceived as a valuable traditional Chinese medicine in China. Currently, much attention also has been paid to ginsenosides, the main active ingredients extracted from g
1. Introduction On July 2023, the World Health Organization (WHO) has classified the soda sweetener aspartame as a possible carcinogen, but said that aspartame is safe to consume with
Myocardial mitochondria are primary sites of myocardial energy metabolism. Mitochondrial disorders are associated with various cardiac diseases. Mitochondrial translation defects cause not only mitochondrial
Betennelsesreaksjonen og forstyrrelsen av hudbarrieren forårsaket av oksidativt stress spiller en avgjørende rolle i prosessen med atopisk dermatitt (AD). Lipidperoksidasjonsnivåene er ofte høyere hos AD-pasienter, mens antio
Vitamin D og B3 (niacin) kan hjelpe immunaktivering og CD4+ T-cellerekonstitusjon i INR-er. NAD, som er avgjørende for cellulær funksjon, avtar med alderen og knyttes til ulike sykdommer. NAD-boostere som NMN, NR og NAM show prom
Sepsis, marked by dysregulated infection response, lacks effective treatment. NAD+'s role in inflammation remains unclear. NAD+ transport challenges limit its therapeutic impact. Novel NAD+-loaded nanoparticles (NPs)
I klinisk diagnostikk er enzymer viktige biokatalysatorer, og de spiller en nøkkelrolle i mange biokjemiske reaksjoner. Disse enzymene krever koenzymer, det vi kaller diagnostiske reagenskoenzymer, for å utføre sine funksjoner.
Blod-hjerne-barrieren (BBB) er en kritisk komponent i sentralnervesystemet som regulerer utvekslingen av molekyler mellom hjernen og blodbanen. Aldersrelaterte endringer i BBB kan føre til økt per
Vaskulær demens er et av de alvorlige og IRreversible syndromene ved ervervet intelligenssvikt forårsaket av en rekke cerebrovaskulære sykdommer. Citikolin er den deriverte av nukleo-siden, som ikke bare kan ekshi
In the quest for a healthier lifestyle, the sweetener debate continues to rage. While sugar has long been the default choice, its adverse health effects have prompted a search for alternatives. One such swe
The nicotinamide adenine dinucleotide (NAD+ )/reduced NAD+ (NADH) og NADP+/reduced NADP+ (NADPH) redox couples are essential for maintaining cellular redox homeostasis og for modulating numerous biologic
Hypertensjon er et stort globalt helseproblem, knyttet til millioner av dødsfall på grunn av hjerte- og karsykdommer. Det innebærer endotelial dysfunksjon og arteriell stivhet, noe som bidrar til åreforkalkningssykdommer. Forbedring av VA
Sukkerrike dietter har ført til en økende forekomst av ulike kroniske sykdommer, inkludert fedme, diabetes, hjerte- og karsykdommer og høyt blodtrykk, noe som utgjør en betydelig global folkehelseutfordring. Stevia Rebaudiosid
CFS is a disorder of unknown etiology, consisting of prolonged, debilitating fatigue, og a multitude of symptoms including neurocognitive dysfunction, flu-like symptoms, myalgia, weakness, arthralgia, low-grade fev
Alkohol er en type psykoaktivt stoff som har vært vanlig brukt i flere kulturer i århundrer. Alkoholinntak er hovedårsaken til akutt leverskade og kronisk leversykdom. Alkoholisme kan akselerere mennesket
Stevia (Stevia rebaudiana Bertoni), en flerårig busk i Compositae-familien, dyrkes i mange regioner over hele verden. Den er kjent for sin sødme, som skyldes tilstedeværelsen av steviolglykosider, som inneholder 1
Steviosid er et naturlig søtningsmiddel utvunnet fra steviaplanten. Den har høy sødmeintensitet og lavt kaloriinnhold, noe som gjør den attraktiv for diabetikere og ogre på karbohydratkontrollerte dietter. Men stevios
Highlight: In chronic HBV infection elevated ROS production is associated to high DNA damage in HBV-specific CD8 T cells - Response to DNA damage is dysfunctional - Up-regulation of CD38 og persistent activatio
In the pass decades days, the Open AI og the amazing founder behind AI application both captured attention world widely. But recently, as MIT Technology Review reported, the OpenAI CEO Sam Altman has turned ou
NMNH forsterker NAD+ kraftig og undertrykker glykolyse, TCA-syklusen og cellevekst NAD+ is essential for biological processes such as metabolism og DNA repaIR, og its decline is associated with age-related diseas
Ginsenosids on Cancer og Related Clinical Studies Cancer is a leading cause of death globally, og its treatment often involves a combination of surgery, chemotherapy, og radiation therapy. These treatm
Vekstkoblet enzymingeniørkunst gjennom manipulering av redoks-kofaktorregenerering An increasingly wide range of chemicals are now being produced from renewable feedstocks through biotechnological means. Biopro
Supervision Policies for NMN in Japan, China, America, Australia og Canada The mainstream researches of NMN have been conducted since a decade years ago. The United States had already carried out its commerciali
Collections of Clinical Trails on NMN Oral Administation NMN, as one of NAD+ booster family critical members, become increasingly popular on the market in the filed of health pomoting. And to date, there are
Med epidemikontrollpolitikken som løsnes globalt, har innbyggere i Kina, India, Malaysia, Japan og Singapore opplevd mangel på medisiner i varierende grad. Men på den annen side, typen medisiner av
Attention! The Cambridge University Researchers Found Ursodeoxycholic Acid (UDCA) Can Prevent og Treat Covid-19 The International academic journal Nature published an article titled FXR inhibition may protect from SARS
Den 10. august 2021 publiserte forskere fra Shanghai University of Science og Technology en artikkel med tittelen NAD+-tilskudd forsterker tumordrepende funksjon ved å redde defekt TUBBY-mediert NAMPT-transkripsjon
